Stem Cells and Bone Tissue

Gaining knowledge on the nature and application of stem cell sciences is a prerequisite for understanding their potential in treating or preventing bone disorders. This book addresses these issues in three sections: Introductory Text and Sources of Stem Cells for Skeletal Tissue, Cellular and Molecular Aspects, and Conditions, Applications, Treatments and Repairs. Coverage includes general aspects of stems cells, sources of stems cells, isolation and purification, applications in regeneration, nanoscale topography, myostatin signalling, chromatin remodelling, osteoporosis, and many other areas.

Stem cells potentially offer a novel therapeutic platform to treat bone disease. They also help the scientist understand the molecular and cellular aetiology of bone disorders. Gaining knowledge on the nature and application of stem cell sciences is a prerequisite for understanding their potential in treating or preventing bone disorders. Stem Cells and Bone Tissue is designed to address these areas in three sections:

• Introductory Text and Sources of Stem Cells for Skeletal Tissue



• Cellular and Molecular Aspects



• Conditions, Applications, Treatments and Repairs

Coverage includes general aspects of stems cells, sources of stems cells, isolation and purification, applications in regeneration, nanoscale topography, myostatin (GDF-8) signalling, c-Jun, Lnk, cell-derived Factor 1/CXCR4, chromatin remodelling, osteoporosis, osteoarthritis, hypophosphatasia, osteopetrosis, osteogenesis, and many other areas of merit too numerous to mention.