Modeling Inhibitors of Matrix Metalloproteinases

This book covers various modern molecular modeling methodologies particularly related to matrix metalloproteinases inhibitors (MMPIs). The text comprises an in-depth description of ligand-based drug designing (LBDD) and structure-based drug designing (SBDD) modeling strategies for designing potential and target specific or selective MMPIs.

Matrix metalloproteinases (MMPs) have been established as promising biomolecular targets for novel drug design and discovery against numerous major disease conditions including various cancers, cardiovascular, neurodegenerative, inflammatory diseases, and more. This book covers various modern molecular modeling methodologies particularly related to MMP inhibitors. Included in the text are descriptions of ligand-based drug designing and structure-based drug designing modeling strategies for designing potential and target specific or selective MMPIs. This book will benefit those who are looking for an in-depth text on the design and discovery processes of novel and selective MMPIs.

Features

Describes modeling strategies applied to MMPs
Elaborates on the designing strategies of MMPs specifically
Includes in-depth analyses of related case studies
Acts as a guide for medicinal chemists, not only from pharmaceutical industries, but also from academia
Covers various modern molecular modeling methodologies, particularly related to MMPIs

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