Microbial Genomics and Drug Discovery

This book presents a broad range of microbial genomics-based approaches to the problem of identifying novel antibiotic classes, focusing on different aspects of the problems presented in identifying, selecting, and prosecuting novel antibacterial targets.

Exploring innovative routes of drug discovery in the postgenomic era, Microbial Genomics and Drug Discovery examines bioinformatic and genomic approaches for the identification, detection, selection, and validation of new antibacterial targets and vaccine candidates. The book discusses potential pathways for effective infection control, inhibition of antibacterial resistance, and acceleration of the drug discovery process. This comprehensive reference describes procedures to recognize common targets in various bacterial species for the design of broad-spectrum antibiotics and clearly illustrates the use of pathway tools in a genomics-based drug discovery project.

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