Mass Spectrometry in Cancer Research

While covering the principles and techniques of mass spectrometry, this book also discusses relevant concepts of cancer medicine and biology. It details the identification, metabolism and dosimetry of carcinogens as well as the pharmacokinetics and metabolism of antineoplastic agents.

Cancer research is becoming multidisciplinary. The complex structural and therapeutic problems require synergistic approaches employing an assortment of biochemical manipulations, chromatographic or electrophoretic separations, sequencing strategies, and … more and more mass spectrometry.

Mass Spectrometry in Cancer Research provides a broad examination of current strategies and techniques and their application to the study of:
(i) occupational and environmental carcinogens;
(ii) antineoplastic and chemopreventive agents;
(iii) pertinent proteins, lipids, nucleic acids and glycoconjugates. Also included are a chapter on instrumentation and methodologies for biologists and physicians and a brief review of the relevant concepts of cancer biology and medicine for mass spectrometrists.

This book is intended for: mass spectrometrists in research or those providing core services; researchers in biological, medical, pharmaceutical or environmental sciences; physicians in academic medicine; and academic/industrial research managers.