Drug-Induced Valvular Heart Disease

by Bernard Cosyns , Bram Roosens , Dirk Kerkhove , Guy Van Camp , Steven Droogmans

Book Details

Format Paperback / Softback

ISBN-10 1616689781

ISBN-13 9781616689780

Publisher Nova Science Publishers Inc

Imprint Nova Science Publishers Inc

Country of Manufacture US

Country of Publication GB

Publication Date May 23rd, 2011

Print length 52 Pages

Weight 98 grams

Dimensions 13.90 x 21.20 x 0.50 cms

Product Classification: Cardiovascular medicine

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The notion that drugs can induce valvular heart disease (VHD) has occurred since the sixties and has received a lot of attention in recent years. Overstimulation of the serotonin 2B receptor (5-HT2B) leads to valvular fibroblast proliferation and thickening of the valvular leaflets with reduced mobility and regurgitation as a consequence. This book focuses on different aspects of this distinct kind of valvulopathy including pathophysiology of drug-induced VHD, histopathological and echocardiographic characteristics,drugs associated with VHD, the influence of cumulative drug dose and risk factors and others.

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