Discrete Optimization for TSP-like Genome Mapping Problems

by A Korol , D Mester , D Ronin , M Frenkel , W Raa , Z Braysy

Book Details

Format Paperback / Softback

ISBN-10 1616681705

ISBN-13 9781616681708

Publisher Nova Science Publishers Inc

Imprint Nova Science Publishers Inc

Country of Manufacture US

Country of Publication GB

Publication Date May 18th, 2010

Print length 62 Pages

Weight 132 grams

Dimensions 23.00 x 15.40 x 0.60 cms

Product Classification: DNA & Genome

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This book introduces a discrete optimisation technique in four applications: classic Traveller Salesperson Problem (TSP), Multilocus Genetic Mapping, Multilocus Consensus Genetic Mapping, and Physical Mapping. Each of the four sections contains the problem formulation, description of the algorithm, and experimental results. The foregoing problems are solved on the basis of Guided Evolution Strategy (GES) algorithm. The algorithm was implemented in MultiPoint package (http://multiqtl.com). The developed analytical tools were applied in many genome mapping projects.

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