Cancer Stem Cells in Lung Cancer
Book Details
Format
Paperback / Softback
ISBN-10
1617282952
ISBN-13
9781617282959
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Aug 23rd, 2011
Print length
65 Pages
Weight
120 grams
Dimensions
21.60 x 14.20 x 0.60 cms
Product Classification:
Oncology
Ksh 9,550.00
Not available
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Quality
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Of the many markers for cancer stem cells (CSCs) in lung cancer reported to date, the cell surface antigen CD133, nuclear ß-catenin accumulation, the side population phenotype, and high aldehyde dehydrogenase (ALDH) activity seem to be most reliable. This book reviews the results of studies on lung CSCs and discusses the significance of these markers from a biological, pathological, and clinical viewpoint. Twenty-seven lung cancer cell lines (nine small cell lung carcinoma (SCLC) cell lines and eighteen non-small cell lung carcinoma (NSCLC) cell lines) were examined for mRNA and protein expression and fractions of cells with activity.
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